Fmoc-L-Leucine

CAS No.: 35661-60-0

product details:

Purity: 99%

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1.What is the Fmoc-L-Leucine ?

Fmoc-Leu-OH can be used as a reactant to synthesize:Various oligopeptides by reacting with functionalized α-amino acid hydrochloride salts.A cyclic depsipeptide sansalvamide A, a natural product found in marine fungus.Streptocidin A?D, decapeptide antibiotics naturally found in Streptomyces?sp. Tü 6071.Coumaroyl dipeptide amide that can be used for cosmetic applications.

L-leucine
61-90-5,21675-61-6,25248-98-0,70-45-1

L-leucine

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
82911-69-1

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

Fmoc-Leu-OH
35661-60-0

Fmoc-Leu-OH

N-Fmoc-β-alanine
35737-10-1

N-Fmoc-β-alanine

9-Fluorenylmethanol
24324-17-2

9-Fluorenylmethanol

Conditions
Conditions Yield
With water; potassium carbonate; In acetonitrile; at 20 ℃; for 6h;
70 %Chromat.
10 %Chromat.
22 %Chromat.
(fluorenylmethoxy)carbonyl chloride
28920-43-6

(fluorenylmethoxy)carbonyl chloride

(R)-2-Amino-4-methyl-pentanoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide
170642-24-7

(R)-2-Amino-4-methyl-pentanoic acid ((1S,2S)-2-hydroxy-1-methyl-2-phenyl-ethyl)-methyl-amide

pseudoephedrine
90-82-4,7009-81-6,90-83-5,6912-63-6

pseudoephedrine

N-(9-fluorenylmethoxycarbonyl)-D-leucine
35661-60-0,126727-03-5,114360-54-2

N-(9-fluorenylmethoxycarbonyl)-D-leucine

Conditions
Conditions Yield
With sodium hydroxide; sodium hydrogencarbonate; Yield given. Multistep reaction; 1.) reflux, 2.) 1.5 h;

2.What is the CAS number for Fmoc-L-Leucine ?

The CAS number of Fmoc-L-Leucine is 35661-60-0.

More information of Fmoc-L-Leucine 35661-60-0 are:

CAS?Number

35661-60-0

Density

1.207 g/cm3

Melting Point

152-156 °C(lit.)

Boiling Point

559.8 °C at 760 mmHg

Flash Point

292.4 °C

Vapor Pressure

2.28E-13mmHg at 25°C

Refractive Index

-25 ° (C=1, DMF)

HS CODE

2922.49

PSA

75.63000

LogP

4.41530

Pka

3.91±0.21(Predicted)

3.What are another words for Fmoc-L-Leucine ?

Synonyms?for?Fmoc-L-Leucine 35661-60-0:N-(9-Fluorenylmethoxycarbonyl)-L-leucine;2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4-methylpentanoic acid;Fmoc-Leu-OH;

4.What is the molecular formula of Fmoc-L-Leucine?

The chemical formula of ?Fmoc-L-Leucine is?C21H23NO4 which containing 21 Carbon atoms,23 Hydrogen atoms,1 Nitrogen atoms and 4 Oxygen atoms,and the molecular weight of??Fmoc-L-Leucine?is 353.418.

5.What is Fmoc-L-Leucine (35661-60-0) used for?

Fmoc-L-Leucine, also known as Fmoc-Leu-OH, is an amino acid derivative characterized by its white to light yellow crystal powder appearance. It is a crucial component in peptide chemistry and holds potential as a novel PPARγ ligand, which can activate PPARγ in various ways. This activation has been linked to reduced osteoclast differentiation, making Fmoc-L-Leucine a more promising therapeutic target in diabetes management compared to traditional antidiabetic drugs.

InChI:InChI=1/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/p-1/t19-/m1/s1

Relevant articles related to Fmoc-L-Leucine:

Article

Source

Fungal Dioxygenase AsqJ Is Promiscuous and Bimodal: Substrate-Directed Formation of Quinolones versus Quinazolinones

Einsiedler, Manuel,Jamieson, Cooper S.,Maskeri, Mark A.,Houk, Kendall N.,Gulder, Tobias A. M.

supporting information, p. 8297 - 8302 (2021/03/01)

Determination of Chemical and Enantiomeric Purity of α-Amino Acids and their Methyl Esters as N-Fluorenylmethoxycarbonyl Derivatives Using Amylose-derived Chiral Stationary Phases

Islam, Md. Fokhrul,Adhikari, Suraj,Paik, Man-Jeong,Lee, Wonjae

, p. 332 - 338 (2019/04/13)

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