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1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one

CAS No.: 25324-52-1

product details:

Purity: 99%

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1.What is the 1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one ?

Used in Pharmaceutical Industry:
1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one is used as a precursor for the synthesis of pharmacologically active compounds due to its phenothiazine core structure and ketone functional group, which contribute to its potential antipsychotic and antiemetic properties.
Used in Chemical Industry:
1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one is used as a building block in organic synthesis for creating more complex molecules, leveraging its ketone group's reactivity and the phenothiazine structure's potential for medicinal properties.

2-acetylphenothiazine
6631-94-3

2-acetylphenothiazine

methyl iodide
74-88-4

methyl iodide

2-Acetyl-10-methylphenothiazine
25324-52-1

2-Acetyl-10-methylphenothiazine

Conditions
Conditions Yield
2-acetylphenothiazine; With potassium tert-butylate; In N,N-dimethyl-formamide; at 20 ℃; for 3h;
methyl iodide; In N,N-dimethyl-formamide; at 20 ℃;
70%
With tetrabutylammomium bromide; potassium carbonate; potassium iodide; In acetonitrile; at 82 ℃;
66%
2-acetylphenothiazine; With potassium tert-butylate; In N,N-dimethyl-formamide; at 20 ℃; for 3h;
methyl iodide; In N,N-dimethyl-formamide; at 20 ℃;
60%
With methanol; at 120 ℃;
In methanol; at 110 ℃; for 24h;
2-acetylphenothiazine
6631-94-3

2-acetylphenothiazine

2-Acetyl-10-methylphenothiazine
25324-52-1

2-Acetyl-10-methylphenothiazine

Conditions
Conditions Yield
Multi-step reaction with 4 steps
1: 93 percent / BF3 *OEt2 / benzene / 36 h / Heating
2: n-BuLi / hexane; tetrahydrofuran
3: tetrahydrofuran / -40 - 20 °C
4: HCl / tetrahydrofuran / 3 h
With hydrogenchloride; n-butyllithium; boron trifluoride diethyl etherate; In tetrahydrofuran; hexane; benzene;
Multi-step reaction with 2 steps
1: 93 percent / BF3 *OEt2 / benzene
With boron trifluoride diethyl etherate; In benzene;

2.What is the CAS number for 1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one ?

The CAS number of 1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one is 25324-52-1.

More information of 1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one 25324-52-1 are:

CAS?Number

25324-52-1

Density

1.226g/cm3

Boiling Point

444.1°Cat760mmHg

Flash Point

222.4°C

Vapor Pressure

4.39E-08mmHg at 25°C

Refractive Index

1.647

HS CODE

2934300000

PSA

45.61000

LogP

4.18670

3.What are another words for 1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one ?

Synonyms?for?1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one 25324-52-1:Ketone,methyl 10-methylphenothiazin-2-yl (8CI); 2-Acetyl-10-methylphenothiazine;2-Acetyl-N-methylphenothiazine

4.What is the molecular formula of 1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one?

The chemical formula of ?1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one is?C15H13 N O S which containing 15 Carbon atoms,13 Hydrogen atoms,1 Nitrogen atoms,1 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of??1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one?is 255.34.

5.What is 1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one (25324-52-1) used for?

1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one is a chemical compound characterized by a phenothiazine core structure and a ketone functional group. It is recognized for its potential in pharmaceutical and medical applications, primarily as a precursor for synthesizing other pharmacologically active compounds. The phenothiazine structure suggests its potential to exhibit antipsychotic and antiemetic properties due to its ability to block dopamine receptors in the brain. The ketone group also indicates its utility in organic synthesis, making it a valuable building block for constructing more complex molecules. 1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one has a wide range of applications in both the pharmaceutical and chemical industries.

InChI:InChI=1/C15H13NOS/c1-10(17)11-7-8-15-13(9-11)16(2)12-5-3-4-6-14(12)18-15/h3-9H,1-2H3

Relevant articles related to 1-(10-methyl-10H-phenothiazin-2-yl)ethan-1-one:

Article

Source

Ni-Catalyzed Reductive Allylation of α-Chloroboronates to Access Homoallylic Boronates

Lou, Yixian,Qiu, Jian,Yang, Kai,Zhang, Feng,Wang, Chenglan,Song, Qiuling

supporting information, p. 4564 - 4569 (2021/06/28)

Phenothiazine - Bipyridinium cyclophanes

Bauer, Helmut,Stier, Falk,Petry, Christoph,Knorr, Andreas,Stadler, Christian,Staab, Heinz A.

, p. 3255 - 3278 (2007/10/03)

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